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The fire broke out at about 09:30 GMT
There is major disruption to all West Coast Main Line railway services between Euston station and Watford Junction due to a fire in north London.
About 70 firefighters are tackling the blaze, which started at about 09:30 GMT at a commercial building on Regent's Park Road in Chalk Farm, London Fire Brigade (LFB) said.
National Rail said to expect major delays until at least 15:00 and Avanti West Coast is advising passengers to use tickets with other operators. London Northwestern Railway trains are also suspended from Euston.
Services to cities including Birmingham, Manchester, Liverpool and Glasgow are affected.
X/@Pramstead_
Firefighters are tackling the blaze with a 32m turntable ladder
Prof. Hirak K Patra
Smoke from the fire could be seen from a mile away at the Royal Free Hospital
Southern trains are not running between Clapham Junction and Watford Junction until further notice and London Overground services between Richmond/Clapham Junction and Stratford and from Gospel Oak to Barking may also be affected.
Half of the one-storey building is alight, LFB said, and Adelaide Road is closed between Winchester Road and Haverstock Hill. The cause of the fire is not known.
